Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1765092852&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=IwkkVpNe4lN05tgL9pL~LQ9KcuDB7yC2QgEzXcnr8-qDoZpa9eOO5tBupFHnrnY-M4~WTvQkkL6CncY~czo3EjtCD5WBX2c6-m5k8oO1jYdOE-7JKJFEL9E0W1kERAP~0Jl-lfh8HfDhVvV74Cp2GcD95qHvYThMG2nJZ8VqDojQSycyFJ7Gh1Egp6gEmaLwTtj-l49ejXTpdtA-gNOlyLLO0bd4UelCcCMT~64PJebkBIq1OilZ4LwlgOBr7nV3k9nX9iK3agQjtsd6P8JTeu2-q27nhsxQEaoNyVevloZtiih0rc6CrJKsOW8L4Jmr~rO-LbI00tTenhCgjUJoew__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1765092852&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=PhXzXa7MzNsaizAwrfhivAAj~kbN8iqWM5mPC32d~HL13g7MPOAlopkcIfJ8k6D9LFFBhpRv9gHh-szf~EI2z6H3fYO9YcKOn6jz~W43IMdviPJsVL9JJKa95yluK80rva16QxX1KhhD4Bdmz~KAmh~tlSoD5xSYFjcrEVd3-BRLbF7fr3WmRgjaCqA-Hikl3RdEhi7aPknV9MHrIuSwy8Wh-fwx8SPfkiCGcNKVG8bcV4~lLYkZQl2NOhOCpHH7YEHMyZ9I4T17~W1F11hWr~aByHwlEDYpoei-ttWMBeYh097OIFrxaUt0dDXgSaRibY6CVxjap~7lzi8oiRho0Q__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger