Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1765089380&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=fLzFUWIej5jT2TQ3lRAkVI1xvFjhlS3bDwBqwUJt2j0L~UE7~ajT-wQRUbYEB1LzodigU840~mZOGDU8Bw6idTkhb8TkocKDVFV9roJzYAAo1MXTmY6C37haouXw8Yfq4RKhm8Rh~A7-XTW0mBWahAsslmYyG6xHUnuOw4ef~avGAERtIsSDG-K5uCumY1GG1yoG1h~mgpeP-qkBvxd69WgpA3kgB-Tx5wikA~bd6fjjsyH-yGAJRLQ~sNsP6uiBCbx3TIYrycK5VUVC1RQZaArTn6VP3vO1NF2UszU0wTuB14NVte7jdwRxOXidGyVLkOoIS963pnkMJ29UIB5ZyQ__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1765089380&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=UiFSNgvciCScNGD5Jy7IWT-dqQFkyPpCHqMAoOv3jDq5IomZyY6JemgxFXExMa5FaJeyfCbtP00jFyQbR-dThffJ677MrwdPWhCLwf0EQJSFV5htwTVdJ6Xw-5Ik3TrT7yuRj-yODxuJujwB9x6Ozz9jdLvl851frczAYeIzl6xSu01gzmZ1pkgVlcKqkZ3UoTpdy426DHkC5ohjiM8dh5HA2fCX9y2t7zyyXNSo1FG2LRckG5lJ1EEJyscPvWUvGuWL2RmOkfsajNx38TwtAmYXYB7um8zMAR9KFaq9ejShceHjZiRM8j3gaN~p7ugc9blaH6aDg7s~mKmIjKwFvw__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger