Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1765089526&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=JYNzQMN9GbJVlDwTAKTVku6XUvpcTKjKFgkfsz9FGTLC9456-TYvBWwEzZ16eapZZZiLYLYi8YBQZgXbQ5fp4193zAgaktLVFixO9EE5eGAQZVw-2Z495xhKl73ljSPU3~xbWTHyiIrLtWARaXQR91dqCaA-FJqHU~Rp10MGEeaVU55KPxvkD~dCQiF0KzMW13sy9nZmIFLXPwqNfLgkWKxyHxzRfbNfoLhlBx2nAc7jcuATO0VJsIpULONFAVyRAjRqNaPincCDT2yOn2SoPJIzgSXwKBGIm29wmXvGte91zZ6ACiRo0fvYlvRvwITtfnB-uX6GIqaYdBn5N-~rWQ__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1765089526&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ND2oAn7vkaKhilInMUh6vNe3cb93goz8Khun~ilGt5tsxCpcqXEdZRPPsVkkrnhmJCiNblyVIGcOe2yuNFdW9PR5OVekvlS1OLB5i~cZaeL2YGAG-FavbHopxoEJwoVba-uBfmz3uUTwgaZfqvtPd8r1KaCqSlW~5ViWPQIgikoDdCjlcgtFfELRABoxel-Rw7Whad5IiFiQ8NFAqsgh2xznRIWc6-IA5DN04N9GU5QYMs5KW9h1CCfy~Ox3j6WZij3~MGn4oKd5Tg7pYhzg2a4786KpcsWXTdOtvGSA83fozXSqAa8zqli3hSNQ3obnLCJGBWmB7gB32wbjogQ2RQ__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger