Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1770474898&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Cb-WuAy9OcozfedlTOwiedjPYhFSjFcxTOlVuNEyEeukEL6UdXCpRafRNQenkiVzoJMXJXtjMAEfbIqz3kD~WOEaFdi-InqbRzTbCyZfWyPtcNWDtlhXUpjr57hDK8UwYCYTelUeIUU6u8f43x-HsoHPSRqU1wQHLja8rDSgTYTYsM-fo-YzxYlOS3Au5CREliSkCPx49ORbSliofsn5c3-eQG8emIZ5s9~o7lssMHAtcuSd0pslHS7aQD~dwp2-DMpKwBxeXYigATvHOZbpnseSOKdyr0Gpp7vThtNjtar8oZVcbk2derSdVHNb68mpKE5EZ2KD~30LfMKEABjMKQ__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1770474898&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=el5XpeZGUSNgdc3erT7QVlqsqwnAykEY2jbJH1E~Wdlz408I6X-854pMtktCFtwPRccAa0ZgAHyfuW4bLJ-OJymStjPJheuUK2r8VyVuEUBNga5ggrhct4vjsD-8OXjKOlxX3OyH8nVS8YwaMl~Z3iFnOCOLcFL9qzG5RkqkFE2~leKyNi-VJtpM7w~RYBM7ckje04S1q5KHXlMj0kZuRyA6y56dynrgyocXF1RZV-~J4zU48hjK3n1b4kM3AJkhFxxcNZCvfY8sGPIq7JNgwImCW60MhU7s4B69pD1g7rtDS~NkJSzEtZAMsyd~5Zp0InldI906VElODhAGsN8HJA__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger