Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1765087045&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=hgNLveESAV2w2Zxt1-OYQQYx9EtjWXr~a7-U18TB~~YPfS4b~ubNe~X5RgpQ4L-VbgA8EHJ9l84Kwvm70B0c6MIHfOgIj3xNDGeeOMQE~0fpYvjbNL8gx3VssVtBufTPGdkOzga3fIGmZ4QHEbty0ZK6S9MQB~~eGbg4upLU5gbQ7xAR9LUert5kncJffznsQ4Qq9tQsVifpUBRrCKFl7gC8aZAM2zhYH0qQS0d4iGqHuWbP4j0IL0krZOMatw2mekmE4wOrqDGa0X0vvwR~pidkPSnXO6z4XAtZE~QwRZqNaeW-FdgwG3sYRSmJ75g6E3VNDQlVemHqPQTa~uIwRA__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1765087045&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=WEoypIS~rECFl6O-vvCPQ5OYZ3rzTEBQfEV2mQw-Uddw7B9rfJvU6~y8bb3phspmkON0Oun3Cpzd7Sithn3FeS9mNURAgPWUyW7gK57F3YvQvCOUHp74mUICvY6vZ8gWDZEBNvLLwghRvfeyLxPhae1oAwY1RmeotWoGUwAGYCXXsyJouEoS229pcS8x1wOqcbTy-HIDGTWVH5Wnmugwdw9Z~oCDrBW6D~xQxBPykwkSvffiuww2PRfyFLd0YkHFMO3bMdbxL7QqfvKsvjZW3MYAb-AnDSxUAFigLJZK9stvr5voH~kWy2GN7CXXGtrh5kArkVj--xK~2AW5i11vug__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger