Download Cell Ranger ARC | Official 10x Genomics Support

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To set up and run Cell Ranger ARC on Linux, please follow the steps below, or skip download and installation and get started with 10x Cloud Analysis:

Cell Ranger ARC 2.1.0 (Oct 6, 2025)

Chromium Single Cell Software Suite
Self-contained, relocatable tar file. Does not require centralized installation.
Contains binaries pre-compiled for CentOS/RedHat 7.0 and Ubuntu 14.04.
Runs on Linux systems that meets the minimum compute requirements.

tar.gz compression
Download for Linux 64-bit (tar.gz)
File size: 852 MB
md5sum: 64018a2d04f0573a6e9d5d5ed7932d82
curl
wget
```
curl -o cellranger-arc-2.1.0.tar.gz "https://cf.10xgenomics.com/releases/cell-arc/cellranger-arc-2.1.0.tar.gz?Expires=1765089237&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=P3nuE2P1FF72dwarpLUrK3bGfZvIsRQ8QJsN0w9khb3gZnLHNkZczgCOmzYx3qTOckoE2qKQIjXIJh9ld7ccqytsx7TmGj-C5gzOUBltsK50WMUJdLOQ6IfPlUflQ5JL2f02ZfLueMyhCnNnR97Bi9tKcBGdZZHwGvwXnW2ty~llQgiwQZwwdB00QtiO~gQmGrhqaWmnBn0o1Q~sWSYHwIwNxi1KtJ4YmaDfmD0TB56FG6wNwu7Jocee5EF7BdFIChafUPBw1IT1ZyQ1E0Fi~EytSAbQN~mLwlPOkmWH0vyGi3hrllMIxxWzHLF0DaL39djCkWnf-e7LFSdzo3S57A__"
```

tar.xz compression

Download for Linux 64-bit (tar.xz)

File size: 607 MB

md5sum: 8a8b495fad481b7da3e23eef8f99d9a4

curl

wget


curl -o cellranger-arc-2.1.0.tar.xz "https://cf.10xgenomics.com/releases/cell-arc/cellranger-arc-2.1.0.tar.xz?Expires=1765089237&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=lpvmEKU5xKOtXoy2hzpj-UyluSm10eSDOY-Pow2cjkJSy8wfCTmFfWTF3MAyfTu0dpfWqwpamThRYDlfO8LMMutf0muDq2QJzWSR~QFJ1oA0-jF-nBrX6XbdAAPRfuM0HN4Ynx2xuA-rR0pLCvA72cRSPZmhX~EOac4SQuhsHTpE1K~A3JhyI4ub8Nbd~kA3J65VisLFjgJJ-7Xxdk4THwUSXf0TCsBTVP529XUJqBy6lJ8eJYzWQkj3L7-hqp6fTxRbCSjq3pW3u3pEyCOnhWzySVgkjytXaKH~4VAHpKtIUGqlgULV5~zwrEIWXRDi-Wrq0haC-fdL7JdG6Sk4oA__"

Download is unavailable on mobile devices.

Cell Ranger ARC v2.1.0 highlights

Users can now perform automated cell type annotations using Gene Expression libraries.
Includes anonymized telemetry data collection to help 10x Genomics improve product functionality.
Strand information is now included in the `fragments.tsv` file.
Improvements to computational performance.

Previous versions

Release notes

References

Steps to build references

2020-A references & reference release notes

Human reference (GRCh38) - 2024-A
- Human reference (GRCh38) dataset required for Cell Ranger ARC.
Download Human Reference
File size: 14 GB
md5sum: 57a41ecf38b1ec2ef66b3d345ad05839
curl
wget
```
curl -O "https://cf.10xgenomics.com/supp/cell-arc/refdata-cellranger-arc-GRCh38-2024-A.tar.gz"
```
Mouse reference (GRCm39) - 2024-A
- Mouse reference (mm10) dataset required for Cell Ranger ARC.
Download Mouse Reference
File size: 13 GB
md5sum: 25c52a830d5f749558f84e1400c71486
curl
wget
```
curl -O "https://cf.10xgenomics.com/supp/cell-arc/refdata-cellranger-arc-GRCm39-2024-A.tar.gz"
```

Download is unavailable on mobile devices.

Compute Platforms

Compute platforms

View options for compute platforms

System requirements

View the minimum requirements to run Cell Ranger ARC pipelines

Installation

Cell Ranger ARC installation

View instructions on how to install Cell Ranger ARC