Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1765089384&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=eI0xqFYXvoB8kvl7jlpC8E0Vu43Z-RsCXJ1K1yT7IPL1XFaUNYApE6qr40WKYPhq-4xnA8Z02AU~LTxQ7uMGTr0cIYyl21azbCw~vwiZsz01cqTDHuic2BHx3~b~qmA7pTIKMS-7pqx1d9qhlOiVueEkrix88UqXUlhf-g2TDKU3So-7GPC5TVbdUnjeoPld3TZ7txlMvbKleTQkhG8FHxyvo0hC87I5Zw-ma0e9GWClLWwqslyQqu-yfvyErMPPBE0PbKAFO2DjHh04ujnN~4kHMEJLORTXnqtrYzpwJTSREhf9eFP9FBcC8ziGT7X6XHqUvMDVbmtB2pX7A0vEDw__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1765089384&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Gk4QueDHhYOGsDQJ~wVRfBLvwGM9K367orDoDZ1WPkR-2qZXM6kMAkcztaJpwAAArB30uMf4enYmNk69K6YHptY53Al4VNEWI-uQhUybA73Z39tO9DU~RSxSdJ04F8h8xSDxaR4r-Tib0ve~QIcBOzAw9Sb31YqjEYwdh57p5MK-PrsJ3kPrGFtiyxHQDv3-vOmqboclKZQo7hkERUASTmTECf05PfH~jRim7ehJnQzfndpHmUz~RmqQ05UH9dKsPT3luCgEEAI4v6kTGmq3NE5d-QR7vzuyCejZxUl8RLt7Qm765TrI58XbzlnAPd-5hycSTg86GxIh-IWUVJ0jlA__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger