Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1774662998&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=n6MaPZLzXHDlU6Bp-EzZOH-0Q0P4U8y78MzDTwIsz062DSR8ldzmH8sPKgY2bMhM-TWGMjXxB9G8LIbUe7ygloP213oVoTWoKM5l1AmrRKVkkKhSy10gueGGeub3sHLK9S--DhYEP67vs5lhj4Rps4nAZmY9KU9juvB32k7YR2Y0WvBcQ0PwrG3e9ZniEscitWzHgPadTNUV4MI4Ur0mc~D4x7btKsQEPY4h9sdP0NHiIBIXoCMhQLMkBlunfgVzALCSqrixTEQ65jHYdsKSrVd41XhN~vuLtDdypvurcIYNkQzDjCAXWRpuaEfGcGcUmqKaIgvkXeM0E0E5xR8gGQ__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1774662998&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=oJs8Xs0jw83riv2TobzAMoUsl8NTMbzc8jBEbs0XbSwSpKlQf0LOORHqqG-P01K3Ap0aG9D3Epc~jOu8xsakarqWiVyExNYUYU1qaRNB-ct7QXzMOEr87nDvc6RsEJT9jS~vwbmuetqjxaG0Tiwt05W4oLj7QERRUB7NWte4ygTgjrCgxjhHSBU~vUIRRolvesOI-RGbfOl2DX1BSUdaoBvIPCTXA0PtD7fzcZTqNST6u0WNkdmRnxNfx~HAL95J0Mpj01g4eeXh1BVso2MswBjtE0bA21GytZV-fY2hM55RAB-uEdKzGj7ndDiWRefqpNvrj4UxGSmLUunV8eTz5w__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger