Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1770480369&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=bhopG1QgF1GVJIRGTFjh-ilwqFlziDyC1ZJmijVqRwuVk95dyIhAL3443korPOu6LdVwdITNEN2sPjSuKPJsTadk7gqFWxhqJqytTp9OYDt0tORgmg6FZlEzmvQ7ocgFz4hPrHLLckOih3p2EdZpiMYEn7NWiGsn81Aj5bGzXMcpNCPO9AzWdjTYotzw0d5nLPcmS-SPuJyK6iVc~4PV0Cjs4DR~3e1c4d1L6WCUhuilaECAt7IBa0aY4EyPWi3xrhYVvnC802kIUmg68nOOh~lPTEYkvSY3Nr-ssR1Ml-5UN9n8LA0-8pVP32HKLZ0xXT4Lcrp5CCCCYnlx1JkT7A__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1770480369&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=kYdFZzgQQvFKLfxdYhhY0SIn6xe4CTkFS3iJB3A6g-smMMgUfd4JdqSxrdl0cfBj0-~3KMdMp976Bf0dJVa9f-AaHQKJgWdZYsrv5mt6mGTtYkOE6zrNx7MOGkEpTgjV0yzSFJ-dTNvirky41u3Ygvfm0nh7FMTVycmhrJwPio6MMDvGyx253aTrKXMwfPUcQYYAWPzl29ekQqpwjyr6gSbnHHSkY55zW5gKQ7Irdm4F~tmJtd1BI5n756vF5oMC5US-fWYWRcIqKd7zw5w~JI0E1GtUmQsSzxn7av-HxjjVKUjSan9FvxhJl9N3A0X9bDSaiKLE0vjkHhb-najFtQ__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger