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Previous Versions

Previous Versions

Space Ranger 4.0.1 (Jun 12, 2025)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 885 MB
    md5sum: b0beb100947717cee8c7ad0d7a9f0247
    curl -o spaceranger-4.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=CP94B0ge6Lsh8Tp49U6t8RGt1OlySYpJFWlr4WpxTsqUqUg~lKfYeBZgxrAtaSn1WHWUnS43lsi2HMfPRyEonu93U1Y6ITf1lGQZi5FblFDfGmDRSVM8YM6pNiVIAH0peztonFxhFUg3~ExNNsAWxNeg7CdYcht6B0kEkNVgTLtT3xs5ZxEFsNjfrdbMSP1lPNAQGLs7M7LPM36T1Ic92UaLda2kDucnkkn-XbNdNa1Tv3BIAjhLIOAbYtn9Tgai-aTSw4unbIon8PGPWXfJB90YYOuYSLitThwYFMdDLik-B0Hfwz1hUMlCN-eviDZOJVdGRA7LySUUmuRoud4Fyg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 582 MB
    md5sum: 3610ff948a6f8129cf49509f1bb34970
    curl -o spaceranger-4.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=QrMlgvZpd6~K8itL07nWVIETIfMPfyXXO3CIBH6x3Mr4ewVFHvSXLQidTchp5MbnioAxXKJlnaOpDq0gxR3q~lR4Yw5y3Ohj1nbVZIfzffnpyWhgefH~oKEjJBf5ghRjsKrrn0877RO28vCxLadC5qnwK6SNqjJh60oUbhMWJ84blmMUTOvjCvZvtYRTl3yk6joeHuWKOshRX4UBVRXSZD-6Z2zfTFE1WpwhCn5aaVJez2Rx00iNgjtAMe3R09KOmc9xaQJFBe-e9DN55SM4HR0RCDlEUKjMx7EQmI4e4uxXzWIH9aO3Gx-uSnYtsZeYwTCW8i-j4eDJt9KeuhsXhg__"

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Space Ranger v4.0.1 highlights

  • Space Ranger v4.0 now supports Visium HD 3' Gene Expression!
  • Cell and nucleus segmentation are now included for Visium HD and Visium HD 3' data with H&E images.
  • Space Ranger v4.0 now features a new UMI-based registration algorithm for Visium HD and Visium HD 3' data.
  • Starting with v4.0, anonymized telemetry data is collected and sent to 10x Genomics.
Release notes

Space Ranger 3.1.3 (Feb 6, 2025)

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    Download for Linux 64-bit (tar.gz)
    File size: 829 MB
    md5sum: 2cc7128cd538108d2a8a737ec54df484
    curl -o spaceranger-3.1.3.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=d7cm0IzUSLsF3YtE5g5yNAdhT-ruDbxEBHM0ORsDMrNMFA~niuVj6nMLf~U2DspPCrBG9T5RloNaiGRNhwkG6evQ2wKtMZnbl27-6BkTzK6M76o2TAzz4zLsjfGKnraqXy5SDgQXm0CV4W9zuEStHeYKsinsnhNtUvp0ygiRp7ibxXcxQpvuxFXGXDzJOjYIS23gz0Cl7HvGl7IFn9iLoZUIsgHo3eKUBsHQhtFw-93GTrkRm~1tDNUD7aYINQW5Md5ZZ~h3VLu93vGU~FrYZI7rqqayJvleN18QiUrgsJGLqYdbt1~AYcFedbyx3JJh2hdlRbQSG~81KttQY9BCvA__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 529 MB
    md5sum: 2756aa7e3b66139059667117546c41bb
    curl -o spaceranger-3.1.3.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=WXo1FLsKIahuh89IytLd4eyZE1lAeujDk4tUIvXXGDveEgoZynSd-t0OA3tbT65QhF41fPK3sRMNlw0T0T0nxQggxZKp5xeGZ79Is7TX4H3OByuTcOruXTCScokvCO-OmdRZ2j3Dl8X5q8jAJrwGWaYngJFAY5qlG4Pv3uNcGY87kRiNPF6wMATzg68D42etxvQBnl0aIo6J9W0x1jNu0oN7AgOF7L6qKsnUomTkTRGq6Jsw4nRMtNsUB832Gjqr7hGdVsQLSC7MhXzKexchb4~~vrnZbfLHjorUfEaxBeSmHrQ5nxypQC79QeVQimM4oK3zieSu7e7FqjD2wlQ2PQ__"

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Space Ranger v3.1.3 highlights

  • Restored support for AVX1 machines.
  • Other miscellaneous bug fixes.

Space Ranger 3.1.2 (Nov 18, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 867 MB
    md5sum: 949088b1e2cc5bd03079b60a65b41d39
    curl -o spaceranger-3.1.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ADyCYbqaytHiKuP~ylXe9v8RJGA~5qI8zH3qmJtJpyxhtzo9xOVO-GtecAHQLuHQAgHAfa-aXd3wONaqoyCAgxhqoFf6HzIfZ70i3VJeH1VOnc-pSM2LxB4Ggfq19otLR8vhT-EQmkYVZQWt22MKQQU4uXjsn28l-BxVRwKwKqSJi56L1byWAmgpJJ7aTGWF~29BesKKItSqJf~zBTHemIDW7NTbn9X5aloDJFZT4JoFjUYQF1S0QpkSY3LyX~Ka4z7xp50-tD8R8LsPZ20-BJxjvoRUZb7lGCXMpUsSg1hXWTsjekExmtEmcv5fmcaHwD9w99bWq3IMyYnjK7x5rg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 552 MB
    md5sum: 5a923ae250eea2974fd1cef7b2f9c1e2
    curl -o spaceranger-3.1.2.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=c3heNUj4G-~EVDRjXRXqmxrUWnECc~vHweQKT7HMbInafGGLxA9i~cKJ8HIgTIlvIgPQkFS8~zfH81GaU2PyLpvk30w7uj05Q2WS1nHlUV3Fy9-U76zM2LKJbKAxOxviKGz5R0Gp3AqPy42W5CRabcp3ue2R1fiwOrTm2kVXEug6aQE5X0Cp~6JJuYIpHJUNrZ3MYRX4R7woa0x6x-CpQ-X8dMfi4-z-7h5yhy99UIPN1bnpCEuB-meazTcIVS4ZJa48109~6yxDXj-jAF2lhZIv0lJ7gatYo7MOlAdnjVKMeBh7uaPEFxr8RK6QFCp6oh6XLtJ5uH9ABa4w6b8VjQ__"

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Space Ranger v3.1.2 highlights

  • In Space Ranger v3.1.2, the pipeline automatically corrects Visium HD CytAssist images generated with instrument firmware v2.1 to account for a bug that affects registration between gene expression data and the microscope image.
  • Adds metrics “Number of UMIs per mm squared of Tissue” and “Number of Reads per mm squared of Tissue” to the web_summary.html file.

Space Ranger 3.1.0 (Aug 28, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 827 MB
    md5sum: 13a2c82adfb1f1efb737e2be121000d1
    curl -o spaceranger-3.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=axt99TC1OZViLdwSwM-JUi599Ywbs4oqfE63IEmnO6SjLr~2TJ8XsCcVN~pt9jRWwojxm8UGGxjN3K0l~vlKXB3gWtD0Wh2wf7C1HMOuNccSqzkyoU4ydWgmTorC2n9EJkHSQXgl8Q-nTO0EyhLI~eRsDFlwnE~LjbOyDK1S5zEJ7HYsJYNN6gwA9TCBntsFYOCgXe4-Mbow1nrXm7dRd44xp6oxazkwTYqLx4YA2Ki2jDlSCNut-yQGTTKYyjkT4y-XMYtbsW09IsI~LMQEJepVVG3Mto~Z8ixxDKv3d3yJqJYVe9SlCsze-ZCEXfzL1FVlHJXd4Qk2o29NCCH5RA__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 527 MB
    md5sum: 28010d3724e9effc488470a961fe39fd
    curl -o spaceranger-3.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=EYdK6ReHSCuOvmx9N0c1k1iecPNjOiaN44dwFlMJD3QpdcmS2iMldOs3V9RFGPEIynx-0WXtzTB8Yh-Q3pTZ45rsPR~zZeQUZ1IFiUrL-o89HfG0HrqIe3hUcGtYOUpw07gd0kCO1VL0El8Uq7LquJqQ6f3EqEF4crj6woXp~V6~pZ3Y3uwxUurwwiMZKD9t778~0QEM6TQGRSL-wyQlrH9KDS8h3ksusG4v~1hXTaJ0mli~Mk13~Di9cu020wkK44leMn~2WMhhm4FBKXsfLHClfh9TXhyx5NeXBqXBMuN7O1Hbg0NWuFYz4MQMp8IAqsMBaxSN1O0vZQQNcW~SNQ__"

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Space Ranger 3.1.0 highlights

  • In Space Ranger v3.1.0, the pipeline has been overhauled to significantly improve the CytAssist to microscope image registration process.

Space Ranger 3.0.1 (May 31, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 757 MB
    md5sum: ae65e7ffdddbb966277b7d1776f8c63c
    curl -o spaceranger-3.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ZRub9QsUGhRvD4vpja8QFrsSmx9JoEUSrITF3Vgae4EZWY8vY685WICxYurdT23QGzVhM1evUv5gT9cBgtQpYzX2EtmT8krXKPIMFehd2kTHZLwvfFeQyU5OXfsjrxsno8QY4jl9LaHp3mI3b6mXg2Cl7Dks-ubY~xsYsisVYt8IB3erlKPZe-5rPfXFc1VjiRiRQ8QxLGH9-7EMI6nJwfoqgzKMkLJUF8a89~s3aNzvos1prjwSZ6BwzQDgKt2IxCMHrvpdFJZtXzui1xTuHmp2P~qxvDFpcCtrf7T0wRHuCbFgSHgCs1b6sXxFE7mCnTiYYT7VxLlAa3Rjf691fQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 481 MB
    md5sum: 451495ee2074ff9adbac49ff8851ea1b
    curl -o spaceranger-3.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=GE7zHXZW9UUn4MIHAJcBt8J4b0dxsHN5LCHhsX8kUTneWWrRX9y7Fk8kxMLTbnwraKxgLxij7abMd9inFGmeua3qluHxT3Vf35igkNK3ZO8dRC4ZhA4pmDC7ijjQSbKKPwaJHTrkDB4PAjoGLBTL-2ajWV6CWB8PJ7TQoCPy3MCJLoFWljRGqUZ-C71U6hE7jVtk14XAsgbqeYid23ourvz0O2ARo1CQwLNAFPdqJ-ye9STRb7-IuIcQsK2kb3MRK0lON82GGO2EebwxUtfoy9mWX4lKxeZoMsOSNR6U39o0xe~0pVMspakdKsyn80Y4MKnJjX73YuujDx6Xm6duUg__"

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Space Ranger 3.0.1 highlights

  • Space Ranger v3.0 now supports Visium HD!
  • Space Ranger v3.0.1 includes bug fixes and other improvements.

Space Ranger 3.0.0 (Mar 25, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 795 MB
    md5sum: 19f4443f10cf94aff5768bd8968cb214
    curl -o spaceranger-3.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=LP19Pvkx2txSK8Ixp1gk9PvINhZ2bUTSrnTM2OiC8Gkj4DC-M7-nXNZByv4QQz7MVygJhM1LzPisV6JRN-MaGlfz8MYta~JOzr3~HCiVvoXkN1WY90tbOQoVu21cG51NxTmW~tHVj48ieAPLEmO7RJ7Ni7eq0VDfxTV2Lk3OYs7vutC-e807Ol1i4WrcmFY~CcphP6-YQjs2qoK1BM33LfVGALJARbJwwvUTj6xM1pzxXlFAtBxVKVZK4WGCpFVVom483fOXA3b5m7soi0g7uLVsFkwQHN5Ztmzsla0Jqu8c5uPha70y-MYjwxYDgD7GGyXzX6gbxTOeDFFj9oR07g__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 507 MB
    md5sum: cd02b83fe849672066c40a1734819432
    curl -o spaceranger-3.0.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=TLeLgFyna4AYvK-T8HvTuv4lv-9abicoU9d1yrNZl30JttBVLSg2wMWPq~wqSdbJbQ1tq2z~dyILOKCGX~MXucZOLnFCZiGj0Se0qwJzYvMVfv3As~9yLoDRMzjpnxqvYyaRB5y~K4g1WY8PDXsOLyknpgVLaKnWGubicNUTeqa5MxO5wWE5J0wB00kqJQQo89HaDQwpSEW54DHHxXsk94Hz0HXLAHpLsf5U6B0CQJJcKpTALR8dS1JDgIWmyxDaCVOvEubB6GOxTpZD1pYjpTOrDDSn5r4CohJ2Gig3LPkaI4U2B06JIT6RoWLeA73L2dDyrRNJ8zMXRYQpxjaBEQ__"

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Space Ranger 3.0.0 highlights

  • Space Ranger now supports Visium HD!

Space Ranger 2.1.1 (Oct 2, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: 0ef64524af2735bd2a0fc9eef5a605f6
    curl -o spaceranger-2.1.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=gqElz44olpYUV4BSF3Geqjq8Ta7udISkdzwTONLO3LntsaxllNj~l6boDeNwegAWx-lLiOyjAwo9i7SeXPrxiatBA0ivC7QLmB0zWhlpj6wHiNq3cA5pG~2r2DQF0uLJecLrvjnTaEggQWNGGRico2KoAAQv~ZYgqBVPIp1aP3NSu8KCMyjpibCIBkNQu15zqz5icfP5zLXD1L~3s2Mp8CGXyfkHwlk-mMR7DPmSF3vcHfZb-fSR92qqyfo6ewH4QaON2SiIdHU2ceW0GfpngbU4Ipm6TILD3j0DfyAd6wKsL3-0JEV8rTeRpOqkEN3vDjWQ243-aWTUFDH1g0gNJQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: e1204bb11b3589bc5d5af244b51bfc18
    curl -o spaceranger-2.1.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=l8xQaype4jCaZxk8qjZN9my2G6DVxPdmcwMBOjMz7Ze6nHXLQUBvkrnkde2cqLVUj2yGufBChBgYfTCvJAa6CBX0ZXnQo7NTRm7tUgcizausc-WZ0W0ELIhBuCwfYovDwDC3j0edS3ojjGoIabB0cmZm58E3Wn2CI4lLJLvFN2FF-JIWnGN8eXcrr7Dz1IX499y0A2quQwmCTKW8n6MoU2v2bCxKmdq-YIdEatHqmuV-twgcNgA-uTjoZPtSm-Ug4xiqXgbb0olf16lJg7Pebzgcfhbp16wcJSRDO6uSoAMzKJtfD4x9qM1ROrcjl5NAm3QkI8hBfk6xjWiHvZuFqw__"

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Space Ranger 2.1.1 highlights

  • Fixed a bug where 8-bit grayscale images were inadvertently turned into 8-bit RGB color images for tissue registration.

Space Ranger 2.1.0 (May 16, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: ee94c453c44770b2b69d6be46b948e3e
    curl -o spaceranger-2.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=IimSRMkRHb9GwWXYgecdvTsRzoFlBP0gs3nwYyS6U49iPnh0peUha3bNtL0KRB1WUAr2vlrMfdA6AccT02uNirg~KKm51IxB4PEVA8hY~aIONK3xGOMASuO3aaU6t210THBMEPQtpTp2eGSdJU9d-lNk5x28g9IvfNywy4zf9WyecA23ykGaq~MxG1ppKqY0tl6uHYcyS75LAmvg3CKgvPS5ldZZXtBvw2J6-UNA0aE3~2TfiIjGn1eCREZJt02NgjjhtumDlxsShM8L6vsC9i5pyoj2DXP0HybynpEqHrzXlUVgbkYGDGStZ5LVVAH71x6vBUoCa5GfKnIhWgqpug__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: a0d90129a81c41cbdd728e23a4d25161
    curl -o spaceranger-2.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.xz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=IFxSkc1o8~qUFG5QOJSGRxObG0tZutfOzilPUAq1XmCdDb3jSJlruGy~YUCgyGHFxUbcftC~6tEIStkdPXhX9JGMUg9sNapZ2OVahweySqvHQUQmIpuYu9JJAv~DwFiOeO0k3y~pUiZflHmSzSm3aVsrTERpBycfRHh2uAhH2w3gknUhb2CPQjs84a555MOcwuZhbUod~2GajcIlv5WjSI2bjdNsbAQo-fyoNxsU7bBtsCYjuhmacjscC648sSGUmKa7Gnxg8wAfXGceL-47SpQ1HcBB3jttnE9dBLjceYZawNj8VSAOVuYyVLqWdWYFnYHcGalJmMwfJioQYPu1Mg__"

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Space Ranger 2.1.0 highlights

  • New feature: Gene + Protein Expression on Visium CytAssist.
  • New feature: Reference-free spot deconvolution.
  • Added support for bigtiff (btf, tf2, and tf8) image file extensions.

Space Ranger 2.0.1 (Dec 7, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 664 MB
    md5sum: 26151804338ae4d4b44151232bd64b50
    curl -o spaceranger-2.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=CCaiCyEZRUit~cD8xZYp3Zd0qrPFpoDJh62ArJNNEewfpzBF~Nsakrg6tKYZFPlT5gKFPV-seA0C9ShFb5nWn4~NX4wFBba8Vol39qFTQaPBWEJl~PPZon~xyEMQerul176NrQhMdkt0HZEyUlnbFYCVjGqY3GRBdVdn9qXUAgg1eWm06AKtauYPsfu2UaGclQtTGRfTZvaIjpcK-T5d3s8lMM8xmwpr5baxJYSPv6GrJVL58e6HM6hY-D4TQGcqi5xYiTuyje-C1ghcDbpeqMgEiYObRzyGRirOZSv2G1VKphsKxM3ChTi-cvJ5-XHYYM3f2shU-otucPEoHfevJQ__"

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Space Ranger 2.0.1 highlights

  • Reclustering workflow now supports generating a UMAP projection in addition to the t-SNE projection.
  • Visium Image Manual Aligner now includes additional support for images with difficult to detect fiducials.
  • A new Spatial Enrichment table which allows users to sort and filter features by their Moran’s I value for Visium Spatial Gene Expression is added.

Space Ranger 2.0.0 (Jul 18, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 662 MB
    md5sum: aec9ec128c7bc9fbf9fd6d31aa390d4c
    curl -o spaceranger-2.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=c~9HbAJIioDvhH~qtxX67h7cdRekGRwP9Y360eWRlCH3tl8PTvZdYkSUyfZuDeM1XNciHT--50dyfl7eY5tbMeAnkR7RzxTA-knerdyjHhFsGwJEMRkEWN4tyI3wAdr2YOfPgcDEDguHckAoVVXWvQFdJG2MTOSr-z3gDzInX4ayfPEbttZ~FFp7QMLahvgJh0smiN6wZznngzeMxr1nm7NYQ2DKIOmeJ8xFyHKIT1iH9tDkmgu8ideyvJLqj0GjshKKP0JXLX2D1mH77d1o-7e1kOy9LRdSEJngVi6Ial2Z4PI9shj~l3bzbZWYcqY6joD2jwDjF46bWRnZHFWcRg__"

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Space Ranger 2.0.0 highlights

  • Space Ranger now supports CytAssist-enabled Gene Expression analysis and includes image registration between the CytAssist image and the microscope image of the same tissue section.
  • spaceranger count now quantifies fluorescence intensity in the image at every barcoded-spot location.

Space Ranger 1.3.1 (Nov 1, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c2eb73125d9ee731fa825ea3734be1b4
    curl -o spaceranger-1.3.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ZnP0mbUGJSZXGuhWwJCI8y4DBdCZthvvwJOxopKMobPWE6~EnPm6y2Y9KZwAy~9KCsffPjbpY6wyBA6vOwHQpAI1K4lwvap5GyOZ-TZAKvJh3y6cdr5XngSLScyk3sOHkwONZPqI0U3fl-ZOOVEre46XKJ5lWtdQZSWVcFYICPbTjadqqUOI~OPlMosc2HqHznRw4hDpvxhYcqCilGD8imboRw0wPksAdKeFivbgOI8alre696IBRaabA2LrYCZEI68obYIcMFCBUVdFejpQiranYdY29nO~hd410g0LjqpE6oLR~TgJm~4h1bd~ED0ZLWpdSRudfbblJuc2pkgKcw__"

Download is unavailable on mobile devices.

Space Ranger 1.3.1 highlights

  • Adds an alert if image alignment would have produced a different result if the --reorient-images option was specified.
  • Update warning for low fraction of reads confidently mapped to the probe set to be more informative.
  • Unsets additional sysconfig environment variables prior to pipeline execution, which may otherwise interfere with the pipeline conda environment.
  • Fixes an issue with mkfastq when bcl2fastq requires LD_LIBRARY_PATH.

Space Ranger 1.3.0 (Jun 9, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: ede7f98db5adf7785e35ae0508c48f74
    curl -o spaceranger-1.3.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=UcUEvU8fJUFhMe8~6-tNJcA2z7RpoVIQRAh-1DvmJC8CMTG4uIIbDmFIbfMNeLZu1fyewwkcplRJyhgd4cIO-q-9GljdFuwnCotx~XOelBNGKrbwaF~vCfrSPhIEz4YbG5NgMxHAZGJ1-uD~wRmzDo5sEHbfqC1VtF0vMbhwZReMcippz0obRWaDMFFkGnNCnYm3ynvBEn4A8airRs5Jf-5Peq6lI8FHJeq5ChxXWmy3Z32545cNfeOdOMtNypg4e99ux5nhdV8MOgXs-Iqp9vjQEUZ8qRxtQ2HcLL7mOS8YsHR6XFFjW80xLAxAv-Dz3pY~XhLwFAOeDuChukAr5A__"

Download is unavailable on mobile devices.

Space Ranger 1.3.0 highlights

  • The recommended operating systems for Space Ranger 1.3.0 are CentOS 7 or Ubuntu 14 Linux variants or newer. CentOS 6 and Ubuntu 12 are still supported but have been deprecated.
  • Gene Expression analysis from formalin fixed paraffin embedded (FFPE) samples is now available in Space Ranger and is invoked by specifying the --probe-set option when running the spaceranger count command. Space Ranger 1.3.0 or later is required to analyze FFPE data.
  • Space Ranger now calculates the Moran's I spatial autocorrelation metric on a per-gene basis.

Space Ranger 1.2.2 (Feb 3, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 3280a085714ce7c894dc14b76312bcda
    curl -o spaceranger-1.2.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.2.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=GspomtMFx4N2BIkBYehqaOkaOYr3bggLWVJDXYBoEB7oc6~T-UhIl6IowXmWExepH9Heo3dppZJZkLgCmDFnakmrIGIeCMBQ6l4GyFtdR~Llq1bh9S4vaNCCyEjBR8my96zxGpEs2xKsMr3khvkXyT6SvJ~1YviHX3cQZhdRQKCYfQYbPFOFFZz4YVnOrEWwyyQu~OJiNjAJpuB6zqgNWAUdNbENAiMMJXN5PbUyTX2vXBInowPMr~FWCtYYG82u7mo-nOux2S2a12pwfrnt2YUevR5EAjpYZ6JnOS070SXjEdU4UFP8Sshq3Pw5aLdMo6kjWzbc2tnIK~hH6f2u4Q__"

Download is unavailable on mobile devices.

Space Ranger 1.2.2 highlights

  • Adds support for pyramid TIFFs, or TIFFs with multiple pages of the same image at different resolutions.
  • Fixes an issue where targeted samples run against new references would fail preflight.

Space Ranger 1.2.1 (Dec 10, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c24ecfc95c5e4f1c268354c5934da98e
    curl -o spaceranger-1.2.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.1.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=A0iDaUZ46rhhovtGbnYI0auYsD7Ieyt2AcNeQHjmMPN7ei9t6TJoJP314nFQFh1mts32SkYUxzglnP~MxxCdw6oHbGJ7scsbtrrOwbjhFDZjYHXcVr~9oyboIxS-zRr7LFRS6tZkOiKhnJkJp5rdDEDWChpXpZbjWlLjDEc-zX1S4fAdA6ut4Qv2H95VWX26iUa~U2-RH7WtXH6zD09pofq9ejAZaSsi6L9HmT22Q6SDfynqP2OR6gPMdONMarTd9dkbt6Ot6I8vQm6Lk0XLhXoDq3fGVKsp5MHBQ~e-iWs9bw3YfKw0TCwWDZ9UCdXD2ZY~QuhS69UcXxl4uVIK3w__"

Download is unavailable on mobile devices.

Space Ranger 1.2.1 highlights

  • Fixed an issue in aggr where files would fail to be copied on NFSv4 File Systems.
  • Disables multithreading in mkref to address an issue where mkref would fail on hardware without AVX support.
  • Better error handling if the pipeline fails due to a missing .env.json file due to an incomplete copy of the application folder.

Space Ranger 1.2.0 (Oct 27, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: fc21902700779111afc3c813bbb0ff5e
    curl -o spaceranger-1.2.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=YHafnXDF0sOPZed2uXWzi-nsqpUNE1zNAitqSyfBrbOKIXKGsvtTNBQjbA11uCnGmD3VxEUyyYAVQKED0DtGgv8P~aWAKG7ho4MSWjff72HNWV9BD1YC5NdBRmaeWGa0Wyxi8Ev-CNCI6eIL6IulZGyzAgciR9Dxih6~WoWG5vqHuxoVMRlY37n8MWzNFnQk~wVrdTLvipfwHNmBOFXmHyc2NVVKELbwMfFHBRXER57yeJOrXVx6~h4~bvdRwzRGZzSg~KOvr2Qm4EAJahIDbkwm3wC8C3R4eSVOprl0F-7Jb7ePZ5c9VnbGLnMH1ZoUxiWbLa6Q8YzBNo0u0zodcA__"

Download is unavailable on mobile devices.

Space Ranger 1.2.0 highlights

  • Targeted Gene Expression analysis is available in Space Ranger 1.2.
  • Introduces the new spaceranger targeted-compare pipeline for direct comparative analysis of matched parent Whole Transcriptome Amplification (WTA) and Targeted Gene Expression datasets.
  • Includes the spaceranger targeted-depth subcommand to estimate sequencing depths appropriate for Spatial Targeted Gene Expression experiments.
  • A new command line option, --no-bam, instructs the pipeline not to construct BAM files.

Space Ranger 1.1.0 (Jun 23, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 708b93997295db31bc457b3d9af79ca2
    curl -o spaceranger-1.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.1.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=a399kGCl58lvgFKCrYVMBtArPL4X4CoTB2oOCQs8aKeWC7ilAa81NfnZqTlneV9Cj~o6T1ds7GTUboOLouMJVJsPZnzeW8jIso4vBGer8b11TU-ONTObc2JKdPgn1MXQrjhRuEyHr-q--6BMCZItFevh6otwW8v0uRCW-cl50uuypj~j1l3uw2pUxbjv8GlHrPywrbU2M6wx2Gul3N3t7o20F3cupOVzGs75A2GWXvrzlKkeE41xtl6RIBymDaDIWREBTC7FWiIDMpy9gXdQW28uTXmWKnNJpnSiNGXRmqKUdiNtTON909RVsh~5JRnhOuwnlVysj1zywEya7TNTvw__"

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Space Ranger 1.1.0 highlights

  • Support for fluorescence imaging input such as IHC/IF.
  • Aggregation of multiple datasets.
  • Optional automatic rotation of slide images.

Space Ranger 1.0.0 (Dec 2, 2019)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.3 GB
    md5sum: 5cc7fb86d0cbff7df687b11575efb7cb
    curl -o spaceranger-1.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.0.0.tar.gz?Expires=1770481086&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=a-Hqbthk62sPOQIHnr~upeE8TDrLuWPxqA72QAigbv-Cr-JvsoVo4brtcLL6PVcE8MN6uYA-dq7uloYDf4~fbJR5ciEaJJQVV9qBs~MAfZihORbZesszCZ~Vb8CVvP35MGFwGA5dpwGoRjrfX5j4EF4OOEOXWNw35dh6pmde8b3qp~HdjagNdLK~DeVNjaP5BpfVkxb2zSQTiNia4UGooP9aqeDXi9~na4AHiHJE3~JTHaBZ9HoRTyV9zqKg5~2-kmjq0XTbyOOK8YH30jqFHbcysFGOujkY6VhHaTYuwUSo0tBSw5euB1AIuKSy68hhzAYnsnBxwJYxfR6Q2zr98A__"

Download is unavailable on mobile devices.

Space Ranger 1.0.0 highlights

  • Initial release of Space Ranger.